Shirley K Knauer Selected Research

Aspartate Ammonia-Lyase

3/2016	Cleaving for growth: threonine aspartase 1--a protease relevant for development and disease.
1/2011	Bioassays to monitor Taspase1 function for the identification of pharmacogenetic inhibitors.

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Shirley K Knauer Research Topics

Disease

36	Neoplasms (Cancer) 05/2022 - 01/2007
8	Head and Neck Neoplasms (Head and Neck Cancer) 02/2013 - 06/2007
6	Leukemia 01/2022 - 06/2007
5	Squamous Cell Carcinoma of Head and Neck 02/2013 - 09/2007
4	Carcinogenesis 01/2022 - 11/2006
2	Colorectal Neoplasms (Colorectal Cancer) 06/2018 - 01/2007
2	Breast Neoplasms (Breast Cancer) 04/2016 - 06/2007
2	Carcinoma (Carcinomatosis) 03/2015 - 07/2008
1	Neoplasm Metastasis (Metastasis) 05/2022
1	Lymphatic Metastasis 05/2022
1	Wounds and Injuries (Trauma) 01/2019
1	Infections 01/2018
1	Metabolic Diseases (Metabolic Disease) 01/2018
1	Pancreatic Neoplasms (Pancreatic Cancer) 01/2018
1	Adenocarcinoma 01/2018
1	Mesenteric Ischemia 06/2017
1	Prostatic Neoplasms (Prostate Cancer) 08/2015
1	Gastrointestinal Neoplasms (Gastrointestinal Cancer) 10/2012
1	Inflammation (Inflammations) 07/2012
1	Acute Promyelocytic Leukemia 01/2012
1	Acute-Phase Reaction 09/2011
1	Hearing Loss (Hearing Impairment) 11/2010
1	Ovarian Epithelial Carcinoma 07/2008
1	Residual Neoplasm 07/2008
1	Disease Progression 07/2008
1	Ovarian Neoplasms (Ovarian Cancer) 07/2008
1	Lymphoma (Lymphomas) 06/2007

Drug/Important Bio-Agent (IBA)

17	SurvivinIBA 01/2022 - 11/2006
9	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2011
4	Pharmaceutical PreparationsIBA 05/2022 - 01/2012
3	Biomarkers (Surrogate Marker)IBA 05/2022 - 04/2016
3	Biological ProductsIBA 06/2018 - 11/2006
3	Threonine (L-Threonine)FDA Link 03/2016 - 01/2011
3	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 02/2010 - 01/2009
2	LigandsIBA 01/2022 - 01/2020
2	Doxorubicin (Adriamycin)FDA LinkGeneric 12/2018 - 03/2015
2	Phosphotransferases (Kinase)IBA 06/2018 - 01/2018
2	Messenger RNA (mRNA)IBA 04/2016 - 06/2007
2	Aspartate Ammonia-LyaseIBA 03/2016 - 01/2011
2	UbiquitinIBA 08/2015 - 10/2012
2	Cisplatin (Platino)FDA LinkGeneric 02/2013 - 05/2009
2	Histone Deacetylase InhibitorsIBA 07/2012 - 01/2012
2	Valproic Acid (Depakote)FDA LinkGeneric 01/2012 - 01/2012
2	Paclitaxel (Taxol)FDA LinkGeneric 05/2009 - 07/2008
2	Nuclear Proteins (Protein, Nuclear)IBA 09/2007 - 07/2007
1	Peptide Hydrolases (Proteases)FDA Link 01/2022
1	7-hydroxycoumarin (umbelliferone)IBA 10/2021
1	ZincIBA 10/2021
1	Histones (Histone)IBA 01/2020
1	PyrrolesIBA 01/2020
1	MetalsIBA 01/2019
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2019
1	MicellesIBA 12/2018
1	arginyl-glycyl-aspartic acid directed cell adhesion receptorIBA 12/2018
1	pillar(5)areneIBA 12/2018
1	arginyl-glycyl-aspartic acidIBA 12/2018
1	ProdrugsIBA 12/2018
1	Oxaliplatin (Eloxatin)FDA LinkGeneric 06/2018
1	Irinotecan (Camptosar)FDA LinkGeneric 06/2018
1	Interleukin-8 (Interleukin 8)IBA 01/2018
1	Dehydroepiandrosterone (DHEA)IBA 01/2018
1	Sirolimus (Rapamycin)FDA Link 01/2018
1	Dehydroepiandrosterone SulfateIBA 01/2018
1	AndrogensIBA 01/2018
1	Mechanistic Target of Rapamycin Complex 1IBA 01/2018
1	Mechanistic Target of Rapamycin Complex 2IBA 01/2018
1	cytidylyl-(3'-5')-cytidine (CpC)IBA 01/2017
1	Hyaluronic Acid (Hyaluronan)IBA 04/2016
1	Ligases (Synthetase)IBA 08/2015
1	Myeloid-Lymphoid Leukemia ProteinIBA 05/2015
1	human taspase1IBA 05/2015
1	Ribosomal Protein S6 Kinases (S6 Kinase)IBA 03/2015
1	Apoptosis Regulatory ProteinsIBA 03/2015
1	MutagensIBA 03/2015
1	Nuclear Export Signals (Nuclear Export Signal)IBA 02/2013
1	Histone Deacetylase 2IBA 10/2012
1	Ribonucleotide Reductases (Ribonucleotide Reductase)IBA 01/2012
1	Hydroxyurea (Hydrea)FDA LinkGeneric 01/2012
1	Tretinoin (Retinoic Acid)FDA LinkGeneric 01/2012
1	Bcl-2-Like Protein 11IBA 01/2012
1	Drug CombinationsIBA 01/2012
1	Immunoglobulins (Immunoglobulin)IBA 09/2011
1	Gentamicins (Gentamicin)FDA LinkGeneric 11/2010
1	Nitric Oxide Synthase (NO Synthase)IBA 05/2009
1	Transcription Factors (Transcription Factor)IBA 01/2009
1	Nitroprusside (Sodium Nitroprusside)FDA LinkGeneric 07/2008
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 07/2008
1	Carboplatin (JM8)FDA LinkGeneric 07/2008
1	Penicillamine (Cuprimine)FDA Link 07/2008
1	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 07/2008
1	Antisense OligonucleotidesIBA 11/2007
1	Catalytic RNA (Ribozymes)IBA 11/2007
1	Differentiation AntigensIBA 06/2007
1	Protein Isoforms (Isoforms)IBA 06/2007

Therapy/Procedure

15	Therapeutics 05/2022 - 03/2007
4	Drug Therapy (Chemotherapy) 06/2018 - 11/2007
2	Radiotherapy 04/2016 - 01/2007
1	Lasers (Laser) 02/2013
1	Heterologous Transplantation (Xenotransplantation) 02/2013
1	Immunotherapy 06/2007